Título del artículo:

ON THE MOTION OF VERY SMALL BODIES IN WATER WAVES.

The equation of motion of a small isolated body that moves in translational motion through a fluid which is itself in unsteady and nonuniform motion is established on the assumption that actual forces acting on the body can be split up in gravity; a drag component, which accounts for viscosity and vorticity effects; and an inertial force with the same formal expression as the force that would act on the body if the flow were irrotational. A simple expression is derived for the leading order approximation of the velocity of very small bodies in water waves. This solution shows that, at least under certain conditions, the previously proposed hypothesis of some delay time is sound, although this time is not the same, in general, for the vertical velocity component as for the horizontal one. From a practical point of view, owing to the assumptions involved in this derivation, the applicability of the solution must be restricted to suspended sediment particles in low concentrations and to reasonably well-behaved wave conditions, including superposition of linear waves (particularly standing waves and irregular wave fields), slightly nonlinear waves, and weak currents superimposed on waves.

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Journal of Geophysical Research

Título del artículo:

Comparative Virucidal Activities of Essential Oils and Alcohol-Based Solutions against Enveloped Virus Surrogates: In Vitro and In Silico Analyses

The large-scale use of alcohol (OH)-based disinfectants to control pathogenic viruses is of great concern because of their side effects on humans and harmful impact on the environment. There is an urgent need to develop safe and environmentally friendly disinfectants. Essential oils (EOs) are generally recognized as safe (GRAS) by the FDA, and many exhibit strong antiviral efficacy against pathogenic human enveloped viruses. The present study investigated the virucidal disinfectant activity of solutions containing EO and OH against DENV-2 and CHIKV, which were used as surrogate viruses for human pathogenic enveloped viruses. The quantitative suspension test was used. A solution containing 12% EO + 10% OH reduced > 4.0 log10 TCID50 (100% reduction) of both viruses within 1 min of exposure. In addition, solutions containing 12% EO and 3% EO without OH reduced > 4.0 log10 TCID50 of both viruses after 10 min and 30 min of exposure, respectively. The binding affinities of 42 EO compounds and viral envelope proteins were investigated through docking analyses. Sesquiterpene showed the highest binding affinities (from -6.7 to -8.0 kcal/mol) with DENV-2 E and CHIKV E1-E2-E3 proteins. The data provide a first step toward defining the potential of EOs as disinfectants.

Acerca de la revista donde se publicó este artículo:

Molecules (Basel, Switzerland)

Título del artículo:

Toxic Determination of Cry11 Mutated Proteins Obtained Using Rational Design and Its Computational Analysis

Cry11 proteins are toxic to Aedes aegypti, the vector of dengue, chikungunya, and Zika viruses. Cry11Aa and Cry11Bb are protoxins, which when activated present their active-toxin form in two fragments between 30 and 35 kDa respectively. Previous studies conducted with Cry11Aa and Cry11Bb genes using DNA shuffling generated variant 8, which presented a deletion in the first 73 amino acids and one at position 572 and 9 substitutions including L553F and L556W. In this study, variant 8 mutants were constructed using site-directed mutagenesis, resulting in conversion of phenylalanine (F) and tryptophan (W) to leucine (L) at positions 553 and 556, respectively, producing the mutants 8F553L, 8W556L, and 8F553L/8W556L. Additionally, two mutants, A92D and C157R, derived from Cry11Bb were also generated. The proteins were expressed in the non-crystal strain BMB171 of Bacillus thuringiensis and subjected to median-lethal concentration (LC50) tests on first-instar larvae of A. aegypti. LC50 analysis showed that the 8F553L, 8W556L, 8F553L/8W556L, and C157R variants lost their toxic activity (>500 ng·mL−1), whereas the A92D protein presented a loss of toxicity of 11.4 times that of Cry11Bb. Cytotoxicity assays performed using variant 8, 8W556L and the controls Cry11Aa, Cry11Bb, and Cry-negative BMB171 on the colorectal cancer cell line SW480 reported 30–50% of cellular viability except for BMB171. Molecular dynamic simulations performed to identify whether the mutations at positions 553 and 556 were related to the stability and rigidity of the functional tertiary structure (domain III) of the Cry11Aa protein and variant 8 showed the importance of these mutations in specific regions for the toxic activity of Cry11 against A. aegypti. This generates pertinent knowledge for the design of Cry11 proteins and their biotechnological applications in vector-borne disease control and cancer cell lines.

Acerca de la revista donde se publicó este artículo:

International Journal of Molecular Sciences

Título del artículo:

Telecommuting and COVID-19: how has the pandemic changed workers’ perception on physical and mental health?

Due to the current pandemic situation, work from home, or telecommuting, has been implemented as part of public health measures to prevent the spread of SARS-CoV-2. Although this measure was introduced rapidly, it is likely to remain in effect for some time to prevent further outbreaks of COVID-19. Despite being few, various studies have addressed the relationship between telecommuting and workers’ health in the context of the current pandemic. Some aspects observed include fatigue, dietary changes, reduced levels of physical activity, and pain. Other conditions observed are associated with “techno-stress,” namely work overload, invasion of privacy, pace of information technology changes, decreased job autonomy, emotional exhaustion, and being constantly in electronic contact with work. Generally speaking, the COVID-19 pandemic has created a new environment for considering work and family life within the discussion on telecommuting. Likewise, a contextualized understanding of factors related to physical and mental well-being is essential to ensure positive impacts on workers. It is important to develop studies and discussions within organizations that allow knowing, analyzing and reformulating strategies and policies aimed at aspects such as changes in workers’ physical and mental well-being in the pandemic context and the way how occupational environments at home affect these components.

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Revista Brasileira de Medicina do Trabalho

Título del artículo:

Comparison of Strength and Power Characteristics Before ACL Rupture and at the End of Rehabilitation Before Return to Sport in Professional Soccer Players

Background: Strength and power is often reduced on the involved versus contralateral limb and healthy controls after anterior cruciate ligament (ACL) reconstruction, but no study has compared with preinjury values at the time of return to sport (RTS). Hypothesis: Divergent recovery patterns in strength and power characteristics will be present at RTS relative to preinjury baseline data and healthy matched controls. Study Design: Cohort study. Level of Evidence: Level 3. Methods: Isokinetic strength tests, bilateral and single-leg countermovement jumps (CMJ; SLCMJ) were measured before ACL rupture in 20 professional soccer players. These then had surgical reconstruction (ACL group) and completed follow-up testing before RTS. Healthy controls (uninjured group) were tested at the same time as the ACL group preinjury. Values recorded at RTS of the ACL group were compared with preinjury. We also compared the uninjured and ACL groups at baseline and RTS. Results: Compared with preinjury, ACL normalized quadriceps peak torque of the involved limb (difference = -7%), SLCMJ height (difference = -12.08%), and Reactive Strength Index modified (RSImod) (difference = -5.04%) were reduced after ACL reconstruction. No significant reductions in CMJ height, RSImod, and relative peak power were indicated at RTS in the ACL group when compared with preinjury values, but deficits were present relative to controls. The uninvolved limb improved quadriceps (difference = 9.34%) and hamstring strength (difference = 7.36%) from preinjury to RTS. No significant differences from baseline were shown in SLCMJ height, power, and reactive strength of the uninvolved limb after ACL reconstruction. Conclusion: Strength and power in professional soccer players at RTS after ACL reconstruction were often reduced compared with preinjury values and matched healthy controls. Clinical Relevance: Deficits were more apparent in the SLCMJ, suggesting that dynamic and multijoint unilateral force production is an important component of rehabilitation. Use of the uninvolved limb and normative data to determine recovery may not always be appropriate.

Acerca de la revista donde se publicó este artículo:

Sports Health

Título del artículo:

Central Oxygen Venous Saturation and Mortality in Patients Undergoing Coronary Artery Bypass Grafting

Purpose: Central venous oxygen saturation (ScvO2) has been reported as a prognostic marker of in-hospital mortality when it is below 60% in certain situations. Nevertheless, it has not been widely reported in patients undergoing coronary artery bypass graft (CABG). The study determined the association between ScvO2 and in-hospital mortality in patients undergoing CABG in a high-complexity health institution in Santiago de Cali, Colombia. Patients and Methods: A retrospective cohort study was conducted with patients undergoing isolated CABG. The subject sample included 515 subjects aged 18 years or older. Exposure was defined as ScvO2 <60% upon admission to the intensive care unit (ICU) following surgery. The major outcome was mortality rates after 30 days. Furthermore, exposure variables were measured at preoperative, intra-operative, and postoperative time points. Results: A total of 103 exposed and 412 unexposed subjects were included. The final model revealed a higher mortality risk in individuals with ScvO2 <60% upon ICU admission compared with those with higher saturation levels (relative risk 4.2, 95% confidence interval: 2.4–7.2; p = 0.001). Values were adjusted using variables such as age (>75 years), low socioeconomic stratum, chronic kidney failure before surgery, unstable angina before surgery, ischemia time (>60 min), and intra-operative inotrope use. The primary cause of death was cardiogenic shock (54.7%), followed by sepsis (25.0%) and postoperative bleeding (17.2%). Conclusion: The study identified an association between ScvO2 <60% and in-hospital mortality in patients undergoing CABG.

Acerca de la revista donde se publicó este artículo:

Therapeutics and Clinical Risk Management

Título del artículo:

Essential oil of Cordia curassavica (Jacq) Roem. & Schult: in vitro and in silico evaluation of effects on dengue virus replication and cytokines production

The lack of effective conventional therapies against dengue has created an interest in herbal preparations as alternative therapies. In the present study, in vitro effects of Cordia curassavica essential oil (EO) on both dengue virus replication and cytokine production were examined. Predictions of molecular interactions between EO compounds and virus and cell proteins were performed with AutoDock Vina. The EO inhibited replication of dengue virus serotypes at IC50 < 30 μg/mL, and it reduced 87% TNF-α, 67% IL-8 and 46% IFN-α in LPS-stimulated PBMCs. The main EO compounds were trans-β-caryophyllene (21.4%), germacrene D (17.8%), α-copaene (16.5%), trans-β-guaiene (8.2%), and α-pinene (6.0%). The first two compounds, δ-cadinene, α-muurolene, α-cubebene and β-burbonene were coupled to proteins involved in the TLR-4 cytokine effector pathway. 3,7-Guaiadiene was coupled to the viral E and C proteins. This study demonstrates the potential of C. curassavica EO as a starting point for discovering novel therapeutic for dengue.

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Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas

Título del artículo:

Impacts of the COVID-19 pandemic on the production, distribution and consumption of agricultural products in the department of Norte de Santander, Colombia

The objective of the research was to analyze the impacts of the Covid-19 pandemic on the production, distribution and consumption of agricultural products in the department of Norte de Santander, Colombia. A total of 96 surveys were applied to agricultural producers of 28 products; 99 surveys to traders of 14 products in 5 markets; and 263 surveys to consumers. The results showed high impacts on production costs, availability and prices of agricultural inputs in production; prices and quality of products in marketing; and prices, quantity, frequency and quality of products consumed.

Acerca de la revista donde se publicó este artículo:

Aibi, Revista de Investigacion Administracion e Ingenierias

Título del artículo:

Plants with photosensitizing activity and therapeutic potential in cutaneous leishmaniasis: Hypericin, a promising alternative

Leishmaniasis is a disease endemic to 98 countries, with over 350 million people at risk of acquiring the infection and 12 million people already infected. The numerous disadvantages associated with current treatments encourage a lack of adherence and even abandonment of the disease treatment, resulting in the emergence of drug-resistant strains. These factors have stimulated the search for therapeutic alternatives that are fast, safe, easy to administer and economical. This has resulted in the emergence of ethnobotany, which, along with phototherapy, could become an innovative strategy for finding naturally occurring compounds with leishmanicidal activity. In this context, products such as hypericin could be considered promising candidates in the discovery and development of new treatments. Hypericin is a naturally occurring molecule that has a high quantum yield in its triplet state and efficiently generates reactive oxygen species. These properties could make hypericin an effective leishmanicidal agent when applied over infected tissues and a potential healing agent that provides cosmetic effects favorable to lesion resolution. In addition, its significant advantages in terms of low cost and easy handling make hypericin a favorable alternative to other treatments for managing this disease. © 2013 ACIN.

Acerca de la revista donde se publicó este artículo:

Infectio

Título del artículo:

On some lower bounds for the permutation flowshop problem

The permutation flowshop problem with makespan objective is a classic machine scheduling problem, known to be NP-hard in the strong sense. We analyse some of the existing lower bounds for the problem, including the “job-based” and “machine-based” bounds, a bound from linear programming (LP), and a recent bound of Kumar and co-authors. We show that the Kumar et al. bound dominates the machine-based bound, but the LP bound is stronger still. On the other hand, the LP bound does not, in general, dominate the job-based bound. Based on this, we devise simple iterative procedures for strengthening the Kumar et al. and LP bounds. Computational results are encouraging. In particular, we are able to obtain improved lower bounds for the “hard, small” instances of Vallada, Ruiz and Framinan.

Acerca de la revista donde se publicó este artículo:

Computers and Operations Research

Título del artículo:

Sensitivity of Countermovement Jump Variables in Professional Rugby Union Players Within a Playing Season

ABSTRACT: Howarth, DJ, McLean, BD, Cohen, DD, and Coutts, AJ. Sensitivity of countermovement jump variables in professional rugby union players within a playing season. J Strength Cond Res 37(7): 1463-1469, 2023-The aim of this study was to explore the measurement sensitivity of a wide range of countermovement jump (CMJ) variables to a full European professional rugby union season. A secondary purpose was to compare 3 different data treatment methods for the calculation of CMJ variables. Twenty-nine professional rugby union players (mean ± SD; age 24 ± 4 years, height 183.7 ± 8.0 cm, body mass 101.6 ± 10.7 kg) completed a minimum of 12 CMJ testing sessions on Thursdays-a day preceded by a rest day and a minimum of 96 hours after a match-throughout a season. Measurement sensitivity, quantified by signal-to-noise ratio (SNR), was determined for 74 CMJ variables and was calculated by dividing the signal, (week-to-week variation expressed as a coefficient of variation [CV%]) by the noise (interday test/retest reliability expressed as CV%). We also identified variables which had no overlap between the 95% confidence intervals (CIs) for the signal and the noise. The 3 data treatment methods for comparison were (a) mean output across 3 jump trials (Mean3), (b) single output from the trial with the highest jump (BestJH), and (c) the trial with the highest flight time to contraction time ratio (BestFTCT). Most variables had an SNR >1.0 (Mean3 = 60/74; BestFTCT = 59/74; BestJH = 48/74). Fewer variables displayed a nonoverlap of 95% CIs (Mean3 = 23/60; BestFTCT = 22/59; BestJH = 16/48). Most CMJ variables during a professional rugby season demonstrated a signal that exceeded measured noise (SNR > 1.0) and that using the Mean3 or BestFTCT data treatment methods yields a greater number of variables considered sensitive within a season (i.e., SNR > 1.0) than when using BestJH. We also recommend the calculation of the 95% CIs for both signal and noise, with nonoverlap indicative of a greater probability that the responsiveness of the variable at team level (i.e., SNR) also applies at the individual level. As sensitivity analysis is cohort and environment specific, practitioners should conduct a sensitivity analysis using internal signal and noise data to inform their own monitoring protocols.

Acerca de la revista donde se publicó este artículo:

Journal of strength and conditioning research

Título del artículo:

Necrotizing gastritis as a rare complication in a pediatric patient with acute lymphoid leukemia

Necrotizing gastritis is an infrequent entity with unknown prevalence, the diagnosis is often inci-dental during exploratory laparotomy or autopsies of patients with acute abdomen. Objective: To present a clinical case of necrotizing gastritis, a rare entity that should be taken into account in the context of immunocompromised patients with associated risk factors. Clinical Case: 7-year-old male schoolboy diagnosed with T-precursor acute lymphoid leukemia, finishing induction chemotherapy cycle with PETHEMA 2013 protocol. He presented 12 days of symptoms characterized by epigas-tric abdominal pain and vomiting, initially acute pancreatitis was suspected, ruled out by normapancreatic enzymes and abdominal computed tomography. Due to suspicion of acid peptic disease associated with steroids, treatment with proton pump inhibitors and prokinetics was started. Consi-dering dyspepsia with alarm signs, such as progression of neutropenia, increased C-reactive protein and clinical deterioration, esophagogastroduodenoscopy (EGD) was performed, compatible with necrotizing gastritis, confirmed by histopathology. He received pharmacological management, zero regimen and parenteral support, and progressive improvement was evidenced in imaging controlsAfter fasting for 30 days, enteral nutrition was started, well tolerated, with ambulatory follow-upAfter improvement, chemotherapy plan was completed, highlighting complete remission, withoucomplications after 2 years. Conclusion: Necrotizing gastritis is a rare entity, in the case described the risk factors were immunocompromise, previous management with corticosteroids and cytotoxic therapy, and possibly, exposure to stressful situations during hospitalization. Early diagnosis and treatment determined a favourable prognosis.

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Andes Pediatrica

Título del artículo:

Development model based on usability metrics for the construction of educational mobile applications

Through investment strategies that bet on educational quality, the Colombian government provides mobile devices to the country’s schools. However, the mobile applications in these devices need themes according to the context and educational level, usability, and UX / UI design. They do not promote an improvement in the teaching-learning process. The present work proposes a model so that non-programming teachers can develop mobile educational applications that generate in the student a good “user experience” with high rates of efficiency and satisfaction, and ease of learning. This descriptive study is applied in 10 public educational institutions. After evaluating 3 mobile educational applications with 20 students, it is obtained that the application that emanates from this model presents satisfactory results in each of the metrics that measure usability, where it obtained an efficiency of 88%; likewise, it was the most efficient and the one with the highest level of satisfaction with 82 points. In conclusion, the development model presented is functional, promotes the design of attractive educational mobile applications, uses techno-pedagogical elements, and responds to the needs of the academic context that requires it.

Acerca de la revista donde se publicó este artículo:

Ingeniare

Título del artículo:

Social entrepreneurship: key element in the transformation from fossil to hydrogen energy economies

The energy transition and the environmental impacts resulting from the use of fossil fuels are a reality materialized in different agreements and commitments by all economies worldwide; however, to achieve the goals and sustainable development, new forms of innovation are required to create space for new business models with significant social impacts, in such a way that economic, social, and environmental welfare is not sacrificed. The objective of the current study is to identify how social entrepreneurship enables the energy transition from fossil fuel-based economies to the creation of hydrogen-based economies. The research followed a descriptive qualitative methodology. Within the main results it was found that social entrepreneurship, in addition to fostering spaces for new business models, promotes the integration of actors and socioeconomic agents, which, applied to the different sectors to be decarbonized, would encourage investment oriented towards a fundamental change that leads to a zero-emission society and to the different collateral social improvements.

Acerca de la revista donde se publicó este artículo:

Revista Venezolana de Gerencia

Título del artículo:

Clinical relationship between reactive arthritis and SARS-CoV-2 infection: A scoping review

Introduction: Reactive arthritis (ReA) is a monoarthritis or oligoarthritis that mainly affects the extremities, it can be related to bacterial or viral infections. Currently, COVID-19 has been linked to the development of arthropathies due to its inflammatory component. Objectives: A scoping review of the literature that describes the clinical characteristics of ReA in survivors of SARS-CoV-2 infection. Materials and methods: A systematic review based on the guidelines for reporting systematic reviews adapted for Prisma-P exploratory reviews and steps proposed by Arksey and adjusted by Levan. Experimental and observational studies published in PubMed and Scopus, English and Spanish, which answered the research questions posed, were included. Results: Twenty-five documents were included describing the main clinical manifestations of ReA in 27 patients with a history of SARS-CoV-2 infection. The time from the onset of symptoms or microbiological diagnosis of COVID-19 to the development of articular and/or extra-articular manifestations compatible with ReA ranged from 7 days to 120 days. The clinical joint manifestations described were arthralgia and oedema, predominantly in knee, ankle, elbow, interphalangeal, metatarsophalangeal, and metacarpophalangeal joints. Conclusions: Arthralgias in the extremities are the main symptom of ReA in patients with a history of COVID-19, whose symptoms can present in a period of days to weeks from the onset of clinical symptoms or microbiological diagnosis of SARS-CoV-2 infection.

Acerca de la revista donde se publicó este artículo:

Revista Colombiana de Reumatologia

Título del artículo:

Association Between Uropathogenic Escherichia coli Virulence Genes and Severity of Infection and Resistance to Antibiotics

Purpose: Urinary tract infection (UTI) is the most frequent bacterial infection. Some uropathogenic Escherichia coli (UPEC) genes have been associated with disease severity and antibiotic resistance. The aim was to determine the association of nine UPEC virulence genes with UTI severity and antibiotic resistance of strains collected from adults with community-acquired UTI. Patients and Methods: A case-control study (1:3) (38 urosepsis/pyelonephritis and 114 cystitis/urethritis) was conducted. The fimH, sfa/foc, cvaC, hlyA, iroN, fyuA, ireA, iutA, and aer (the last five are siderophore genes) virulence genes were determined by PCR. The information of antibiotic susceptibility pattern of the strains was collected from medical records. This pattern was determined using an automated system for antimicrobial susceptibility testing. Multidrug-resistant (MDR) was defined as resistance to three or more antibiotic families. Results: fimH was the most frequently detected virulence gene (94.7%), and sfa/foc was the least frequently detected (9.2%); 55.3% (83/150) of the strains were MDR. The evaluated genes were not associated with UTI severity. Associations were found between the presence of hlyA and carbapenem resistance (Odds ratio [OR] = 7.58, 95% confidence interval [CI], 1.50–35.42), iutA and fluoroquinolone resistance (OR = 2.35, 95% CI, 1.15–4.84, and aer (OR = 2.8, 95% CI, 1.20–6.48) and iutA (OR = 2.95, 95% CI, 1.33–6.69) with penicillin resistance. In addition, iutA was the only gene associated with MDR (OR = 2.09, 95% CI,1.03–4.26). Conclusion: There was no association among virulence genes and UTI severity. Three of the five iron uptake genes were associated with resistance to at least one antibiotic family. Regarding the other four non-siderophore genes, only hlyA was associated with antibiotic resistance to carbapenems. It is essential to continue studying bacterial genetic characteristics that cause the generation of pathogenic and multidrug-resistant phenotypes of UPEC strains.

Acerca de la revista donde se publicó este artículo:

Infection and Drug Resistance

Título del artículo:

Inclusive education. State of the art, research trends and challenges from the Systematic Review of the literature

The objective of this review article was to establish the state of the art and trends in the study of inclusive education, as well as the challenges of this education in the global context. It was a qualitative analysis, under the model of systematic review of the literature, using 20 digital scientific documents in the global context in the period 2017-2023. The analysis process is subdivided into two dimensions: the state of the art and the trends that support an epistemic and methodical orientation of future research. The analysis process is based on hermeneutics through the critical analysis of the documents taken as reference. It is concluded that the concept of inclusive education has not been transformed over time, especially if analysis approaches of the object of study have been integrated with health systems, education systems, global and sectoral public policies, and research. academics, evolving towards understanding disability from special educational needs, which deserve inclusive educational treatment.

Acerca de la revista donde se publicó este artículo:

Aibi, Revista de Investigacion Administracion e Ingenierias

Título del artículo:

House Condition Scoring Scale as a Risk Indicator of Infestation by Aedes in Two Mexican Localities

Mexico has shown an increase in dengue incidence rates. There are factors related to the location that determine housing infestation by Aedes. This study aimed to determine factors associated with housing infestation by immature forms of Aedes spp. in the dengue endemic localities of Axochiapan and Tepalcingo, Mexico, from 2014 to 2016. A cohort study was carried out. Surveys and inspections of front- and backyards were conducted every 6 months, looking for immature forms of Aedes spp. A house condition scoring scale was developed using three variables (house maintenance, tidiness of the front- and backyards, and shading of the front- and backyards). Multiple and multilevel regression logistic analysis were conducted considering the housing infestation as the outcome and the household characteristics observed 6 months before the outcome as factors; this was adjusted by time (seasonal and cyclical variations of the vector). The infestation oscillated between 5.8% of the houses in the second semester of 2015 and 29.3% in the second semester of 2016. The factors directly associated with housing infestation by Aedes were the house condition score (adjusted odds ratio [aOR]: 1.64; 95% CI: 1.40-1.91) and the previous record of housing infestation (aOR: 2.99; 95% CI: 2.00-4.48). Moreover, the breeding-site elimination done by house residents reduced the housing infestation odds by 81% (95% CI: 25-95%). These factors were independent of the seasonal and cyclical variations of the vector. In conclusion, our findings could help to focalize antivectorial interventions in dengue-endemic regions with similar demographic and socioeconomic characteristics.

Acerca de la revista donde se publicó este artículo:

The American journal of tropical medicine and hygiene

Título del artículo:

Influence of altitude on the morphology and weight of cocoa beans in the Northern department of Santander, Colombia

Cocoa production is a subject widely studied by researchers, however, the yield behavior and characteristics of cocoa beans at different altitudinal levels have been scarcely addressed in the published scientific literature. The objective of the research was to establish the relationship between the morphology and weight of cocoa beans (Theobroma cacao, L) in relation to 6 altitudinal gradients, from 0 to 1,200 m. a.s.l., in the department of Norte de Santander (Colombia). In each gradient, 5 farms were randomly selected and the 2019 and 2020 harvests were analyzed, for a total of 60 observations. Per sample, we determined the weights and percentage of hulls in 100 dry almonds (n=100) and morphology (length, width and thickness) in 20 dry almonds (n=20). The data were analyzed with descriptive statistical estimators, analysis of variance and Tukey tests. The study determined a positive relationship between altitude, weight and morphology of the almonds with the highest values obtained in the gradient of 801-1000 m.a.s.l. (147.47 g ± 10.36 g) and the lowest between 0-200 m.a.s.l. (130.6 g ± 17.36 g). (130.6 g ± 17.40 g); in the morphology of the kernels, the gradient of 801-1000 m.a.s.l. obtained higher average volumes (2.766 cm3) and the gradient of 201-400 m.a.s.l., lower values (2.452 cm3). The percentage of husk evidenced an inversely proportional relationship with respect to altitude with low values in the gradient of 801-1000 m.a.s.l. (11.08% ± 0.79%) and high values between 201-400 m.a.s.l. (14.05% ± 0.79%) and 201-400 m.a.s.l. (14.05% ± 0.79% ± 0.79%). (14, 05% ± 0, 92%).

Acerca de la revista donde se publicó este artículo:

Aibi, Revista de Investigacion Administracion e Ingenierias

Título del artículo:

From fossil fuel energy to hydrogen energy: Transformation of fossil fuel energy economies into hydrogen economies through social entrepreneurship

Social entrepreneurship plays a crucial role in global sustainable development, enhancing the quality of life and preserving environmental, human, and social capital. However, when it comes to the energy transition, it faces numerous challenges and experiences conflicts in terms of costs, technological innovation, and public policies. This study seeks to illustrate one of the new alternative energy schemes which could replace fossil fuels in the future: hydrogen. This transformation would result in significant social impacts, leading to the question, “how should it be done?” Social entrepreneurship can integrate socio-economic actors and agents and help them to devise and implement new forms of energy innovation. Therefore, a descriptive qualitative methodology was implemented, that allows us to analyze the process of building entrepreneurship with a social vision and to propose a model that enables the transition from fossil economies to the hydrogen economies. Among the most significant results, the importance of the support of the three primary axes of each country and the role of social entrepreneurship as a key element for the transition stand out. The discussion contributes to the debate on the path that academia should lead, and the fundamental role of entrepreneurship based on social conscience as a driver of change.

Acerca de la revista donde se publicó este artículo:

International Journal of Hydrogen Energy

Título del artículo:

Seed priming with microbial inoculants for enhanced crop yield

Advanced technologies are used in modern agriculture, aimed at maximizing crop yield and increasing agricultural output. Modern agriculture is facing new challenges in meeting rising food demands, remaining internationally competitive, and producing high-quality agricultural products. Seed priming is a physiological and presowing method in which seeds are moderately moistened to the point where pregermination metabolic pathways are activated, allowing for quick germination, growth of seedlings, and eventual yield under natural and stressed conditions. Biopriming is the use of a living microorganism’s inoculum to apply plant growth-promoting microorganisms (PGPMs) to seeds. Over the last few decades, inoculation of PGPMs has proven to be a successful and environmentally acceptable approach to increasing the durability of food supply while limiting its ecological impact. This chapter highlights the methods of biopriming based on the superior solutions of PGPM inoculants as an alternative to chemical treatments in current agriculture, which are more eco-friendly for future farming.

Acerca de la revista donde se publicó este artículo:

Microbial Inoculants: Recent Progress and Applications

Título del artículo:

Role of women in the conservation of Cácota pottery as a cultural heritage of Norte de Santander Colombia within the framework of the orange economy

The objective of the research was to reconstruct the ancestral knowledge of ceramics in the municipality of Cácota de Velazco, department of Norte de Santander, Colombia. The methodological approach was based on the Interpretative Paradigm using qualitative methodology through Participatory Revaluation Research (PRI) by means of semi-structured interviews with an intentional sample of 7 women artisans of the community and the recording of the handicraft processes of elaboration of ceramic products. The reconstruction of ceramic knowledge made it possible to value and make visible the participation of women artisans in the cultural and economic activities of the municipality in products of new academic knowledge and in technical documents for institutions related to the development of public policies.

Acerca de la revista donde se publicó este artículo:

Aibi, Revista de Investigacion Administracion e Ingenierias

Título del artículo:

Treatment of acid mine drainage using filters made from steel dust

The treatment of acid mine drainage-AMD is necessary to mitigate the environmental impacts generated in the mining industries, because an inadequate and inefficient treatment system can potentiate a risk to both human health and the environment. In order to promote an innovative and economic method for the treatment of AMD aimed at neutralizing its pH, seven filters were built with steel-making dust and other materials, following the Design Thinking methodology. The results of the investigation showed a neutralization of the pH of a filtered HCl acid solution for twenty days in the built prototypes. The main result of the study showed that the filters built with steel-making dust can neutralize the pH of ADM, a consequence of the presence of calcareous material.

Acerca de la revista donde se publicó este artículo:

Aibi, Revista de Investigacion Administracion e Ingenierias

Título del artículo:

A mathematical model and simulation scenarios for T and B cells immune response to severe acute respiratory syndrome-coronavirus-2

Severe acute respiratory syndrome coronavirus is a type 2 highly contagious, and transmissible among humans; the natural human immune response to severe acute respiratory syndrome-coronavirus-2 combines cell-mediated immunity (lymphocyte) and antibody production. In the present study, we analyzed the dynamic effects of adaptive immune system cell activation in the human host. The methodology consisted of modeling using a system of ordinary differential equations; for this model, the equilibrium free of viral infection was obtained, and its local stability was determined. Analysis of the model revealed that lymphocyte activation leads to total pathogen elimination by specific recognition of viral antigens; the model dynamics are driven by the interaction between respiratory epithelial cells, viral infection, and activation of helper T, cytotoxic T, and B lymphocytes. Numerical simulations showed that the model solutions match the dynamics involved in the role of lymphocytes in preventing new infections and stopping the viral spread; these results reinforce the understanding of the cellular immune mechanisms and processes of the organism against severe acute respiratory syndrome-coronavirus-2 infection, allowing the understanding of biophysical processes that occur in living systems, dealing with the exchange of information at the cellular level.

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Journal of Physics: Conference Series

Título del artículo:

Log-linear modeling between risk factors and interactions for human papillomaviruses infection and papanicolaou smear abnormalities

Modeling qualitative variables and their interactions often require multidimensional analysis through Log-linear models. Furthermore, these models are useful as alternatives in fields where probabilistic classification is required, such as speech recognition or pattern classification. This work uses log-linear modeling as a methodological approach to the analysis of 1114 valid cases of women participating in a human papillomavirus infection and cervical cancer screening program, thus relating a public health problem to biophysical knowledge. The objective of the study was to evaluate the main effects and interactions between the variables compared to the independence model. A backward stepwise selection with a 5% probability of elimination was performed to arrive at the best hierarchical model starting on the covariates that were significant in a previous bivariate analysis. This allows us to understand how biophysical process modeling can identify biomarkers and propose prevention methods for human papillomavirus infection and Papanicolaou smear abnormalities.

Acerca de la revista donde se publicó este artículo:

Journal of Physics: Conference Series