Título del artículo:

Educational management from the integrated input-output methodology of the dynamic model

The purpose is to analyze management in educational organizations through the integrated input-output methodology of the dynamic model with emerging technologies, in the institutions “Camilo Torres Restrepo, San José and San Isidro”, municipality of Curumaní (Cesar-Colombia). The research was of an analytical type; supported by the qualitative macro-ethnographic approach. According to the epistemological framework, the research is considered phenomenological. The technique used was the in-depth interview, applying the interview script directed to nine (9) key informant teachers of the mentioned institutions. In basic secondary education, the integrated input-output methodology of the dynamic model using emerging technologies does not constitute a teacher’s priority to respond to learning mediated by virtuality during Covid-19. Finally, it is necessary for classroom managers to effectively apply the theoretical-practical elements related to the integrated input-output methodology in order to assertively guide students in their learning process.

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Revista Venezolana de Gerencia

Título del artículo:

Social responsibility in teaching practice: an ethical perspective

Social responsibility has established links with the educational sphere through the social contract to which educational institutions are called. In view of these links, the purpose of this research is to analyze the features of the teaching function from the dimension of social responsibility, with an ethical approach. A documentary-type methodology was used with a systematic review of the literature on the subject. Preliminary findings show that educational social responsibility demands a teacher whose ethical traits point to an exercise committed to: the formation and transmission of civic and ethical values, the promotion of the relationship between school-community and its environment, the promotion of an open educational institution without physical or disciplinary boundaries, motivated by the organization of vulnerable social groups and education for sustainable development. Final reflections point to the dissolution of barriers between the school and the community to achieve a just, diverse and sustainable environment.

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Revista Venezolana de Gerencia

Título del artículo:

Management and public policies of the Colombian state for the integration of migration. The case for education

The migratory movement of Venezuelans to Colombia has increased significantly in the last decade. The Colombian state has designed different public policies to regularize the situation of migrants in the country. This paper aims to analyze the public policies formulated by the Colombian state and its management for the social integration of migrants. The methodology consisted of the analysis of legal regulations, programs, projects and plans emanating from the Colombian State bodies, as well as their implementation translated into the level of impact that these public policies can generate for the social integration of migrants. The results show that the regulations account for a public policy that guarantees the right to education by solving the barriers to access to the system, presenting mechanisms to ensure permanence and establishing an identification document such as the PPT for graduation. It is concluded that real public policy management, although at a general level it presents failures in its implementation, these are not the exclusive responsibility of the Colombian state; there are other factors that influence the consolidation of real politics.

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Revista Venezolana de Gerencia

Título del artículo:

Effects of aspirin on cardiovascular outcomes in patients with chronic kidney disease

Patients with chronic kidney disease (CKD) carry a high cardiovascular (CV) risk. Since whether this risk is reduced by aspirin is unclear, we examined if the effect of aspirin on cardiovascular outcomes varied by baseline kidney function in a primary cardiovascular disease prevention trial. The International Polycap Study-3 (TIPS-3) trial had randomized people without previous cardiovascular disease to aspirin (75 mg daily) or placebo. We now examined aspirin versus placebo on cardiovascular events in participants grouped by estimated glomerular filtration rate (eGFR), using a threshold of 60 ml/min/1.73 m2, and by using tertiles of eGFR. The primary outcome was a composite of non-fatal myocardial infarction, non-fatal stroke or cardiovascular death. A total of 5712 participants were randomized with a mean follow-up of 4.6 years. Of these, 983 (17.2%) had an eGFR under 60 ml/min/1.73 m2 (mean eGFR 49 ml/min/1.73 m2) and 4,729 over 60 ml/min/1.73 m2 (mean 84 ml/min/1.73 m2). In participants with an eGFR under 60 ml/min/1.73 m2 there were 26 primary outcomes in 502 participants on aspirin and 39/481 on placebo (hazard ratio 0.57; 95% confidence interval 0.34-0.94). In participants with an eGFR over 60 ml/min/1.73 m2 there were 90 primary outcomes in 2357 participants on aspirin and 95/2372 on placebo (0.95; 0.71-1.27). With tertiles of eGFR under 70, 70-90, and over 90 ml/min/1.73 m2, risk reductions with aspirin for the primary outcome were larger at lower eGFR levels (0.62; 0.43-0.91) for the lowest tertile, (0.96; 0.62-1.49) for the middle, and (1.30; 0.77-2.18) for the highest tertile. Thus, our findings support aspirin may reduce cardiovascular events in people with moderate to advanced stage CKD.

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Kidney International

Título del artículo:

Levels of Anxiety and Stress Experienced by Nurses in Inpatient Units

Objective: To assess state-trait anxiety levels and their correlation with occupational stress and socio-biographical and occupational factors in nursing professionals. Materials and Methods: This is a quantitative, cross-sectional, analytical study conducted in the inpatient units of a university hospital in southern Brazil, with the participation of 162 nursing professionals. For data collection, so-cio-biographical and occupational forms, the Stress-Symptom Scale, the Workplace Stress Scale, and the State-Trait Anxiety Inven-tory were used. The data were analyzed based on descriptive and inferential statistics. Results: Nursing professionals have moderate levels of state-trait anxiety. There is a positive correlation between state-trait anxiety scores, stress scores, and stress dimensions (rho = 0.811, p < 0.001). “Trait” anxiety is associated with years of experience in nursing (PR 0.97) and psychic-mental health follow-up (PR 1.97). “State” anxiety is associated with sex (PR 0.54), education (PR 2.26), and hours of sleep (PR 0.92). Conclusions: “State” anxiety is associated with sex, age, higher education level, and psychic-mental health follow-up; however, years of experience in nursing and hours of sleep were found to be protective factors.

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Aquichan

Título del artículo:

Organizational culture - assertiveness - empowerment of knowledge in the community of the nursing program at the Universidad de Santander Cúcuta campus.

Organizational culture has become a significant element in different organizations of any kind, in this case framed in the linkage that is presented with the nursing program at the University of Santander Cúcuta; because within the trends and managerial innovations arises the need to handle the different concepts and theories that currently make mention of organizational culture to provide nursing professionals with tools and of course components that allow them a better education, training and professional performance. Reason that converges in the following general objective: To analyze the Pedagogical Mediator on the Organizational Culture for the Assertiveness and Empowerment of Knowledge in the Academic Community of the Nursing Program of the University of Santander Campus Cúcuta. The methodology used was framed in mixed approaches (quantitative and qualitative), where a documentary analysis and a description of the variables were worked, plus the appreciations of the key informants, which led to assume a set of knowledge referred to the pedagogical mediator with hypertextual and hypermedial strategies, which allowed dynamizing the academic processes, optimizing time, resources and strengthening the organizational culture to achieve the assertiveness and empowerment of knowledge in the community; which left structured the different ontological components.

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Aibi, Revista de Investigacion Administracion e Ingenierias

Título del artículo:

Diagnostic accuracy of uroflowmetry parameters to predict infravesical obstruction

Objective: to evaluate the performance statistics of average flow (Qave), voiding time (Vtime), and time to maximum flow (TQmax), in addition to maximum flow (Qmax), for diagnosis of infravesical obstruction. Methods: we reviewed urodynamic studies performed in men > 40 years. Obstruction was considered a grade 3-6 in the Schäfer nomogram. Sensitivity, specificity, positive likelihood ratio (LR+), negative likelihood ratio (LR-), and the receiver operator characteristic (ROC) curve were calculated for the different components of free uroflowmetry. Results: we analyzed 432 studies. Patients with obstruction had lower values of Qmax and Qave, and higher values of Vtime and TQmax. Considering different thresholds, Qmax had sensitivity, specificity, LR + and LR-values of 12-83%, 50-97%, 1.7-4.46 and 0.32-0.9, respectively; Qave had sensitivity, specificity, LR + and LR-values of 65-95%, 21-66%, 1.22-1.94 and 0.19-0.53, respectively; Vtime had sensitivity, specificity, LR + and LR-values of 49-85%, 26-67%, 1.15-1.54, and 0.57-0.74, respectively; TQmax had a sensitivity, specificity, LR + and LR-of 36-81%, 22-72%, 1.04-1.33 and 0.85-0.87, respectively. The areas under the ROC curves for Qmax, Qave, Vtime and TQmax were 0.75 (95% CI = 0.71-0.79, p < 0.001), 0.71 (95% CI = 0.66-0.75, p < 0.001), 0.62 (95% CI = 0.57-0.67, p < 0.001) and 0.55 (95% CI = 0.5-0.6, p = 0.03), respectively. Conclusions: Qave, Vtime, and TQmax showed a statistically significant discriminatory capacity to predict infravesical obstruction, and therefore they have clinical value as a complement to the information provided by Qmax.

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Urologia Colombiana

Título del artículo:

Semantic Cloud System for Scaling Data Science Solutions for Welding at Bosch

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CEUR Workshop Proceedings

Título del artículo:

Impairment of performance skills and maturational age in infants due to gestational Zika

Introduction: Zika virus is transmitted by the bite of infected mosquitoes, but can also occur through intrauterine infection before delivery, and the virus passes to the fetus. Objective: to describe the level of impairment in performance skills and maturational age of children in the Courageous of the Future program with neonatal Zika virus infection. Materials and Methods: the research is framed with a quantitative approach of correlational type supported with a field research and non-experimental design, with a sample of 15 infants of 3, 4 and 5 years old. The collection technique used was the Abbreviated Scale. Results: Regarding the areas evaluated with respect to the maturational age, it was found that the weighting of motor skills and praxis found a correlation coefficient of 0,601 (moderate) and in the sample of the execution skills of 3-year-old children with gestational Zika, a correlation of 0,853 (strong) was obtained. Discussion: Zika virus infection in children, acquired during gestation, strongly limits the performance skills characteristic of the maturational age in this population. Conclusions: there is correlation between infants with gestational zika and the strong affectation in the actions or behaviors that a patient has to move and interact physically with activities, objects and therefore perform a learned motor activity.

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Salud, Ciencia y Tecnologia - Serie de Conferencias

Título del artículo:

Leveraging AI Tools for Enhanced Digital Literacy, Access to Information, and Personalized Learning

The digital divide remains a significant challenge for many communi-ties worldwide. However, recent advancements in AI technology offer a unique opportunity to address this divide by enhancing digital literacy, promoting access to information and resources, and facilitating personalized learning experiences. This chapter explores how machine learning algorithms, natural language processing, and other AI-driven technologies can be leveraged to provide more effective and efficient training tailored to individualneeds and learning styles. Additionally, AI tools can provide more accessible and relevant information to individuals regardless of their level of digital competence. By utilizing AI tools to improve digital literacy, promote access to information and resources, and facilitate personalized learning experiences, we can create a dynamic feedback loop that contributes to closing the digital divide. This chapterproposes that this feedback loop can lead to a cycle of empowerment, where the accumulation of knowledge and resources reinforces the ability to learn and acquire more resources. Finally, this chapter provides recommendations on how to effectively and responsibly use AI tools to address the digital divide.

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Understanding Complex Systems

Título del artículo:

B-cell lymphocytosis in relatives of Colombian patients with chronic B-cell lymphoproliferative disorders

Introduction. Monoclonal B-cell lymphocytosis generally precedes chronic lymphocytic leukemia, affecting about 12% of the healthy adult population. This frequency increases in relatives of patients with chronic B-cell lymphoproliferative disorders. Objective. To determine the frequency of monoclonal B-cell lymphocytosis in relatives of patients with chronic B-cell lymphoproliferative disorders, their immunophenotypic/cytogenetic characteristics, a possible relationship with infectious agents, and short-term follow-up in the Colombian population. Materials and methods. Fifty healthy adults with a family history of chronic B-cell lymphoproliferative disorders were studied using multiparametric flow cytometry, cytogenetic/serological testing, lifestyle survey, and 2-year follow-up. Results. The frequency of monoclonal B-cell lymphocytosis found was 8%, with a predominance of female gender and advanced age, increasing to 12.5% for individuals with a family history of chronic lymphocytic leukemia. Three out of four individuals presented chronic lymphocytic leukemia-type immunophenotype, all with low counts. In turn, a significantly higher number of cells/μl is observed in these individuals in T lymphocyte subpopulations, together with a greater predisposition to the disease. The described clonal opulations increase over time in a non-significant manner. Conclusions. The frequency and behavior of monoclonal B-cell lymphocytosis in patients with family history of chronic B-cell lymphoproliferative disorders are like those found in related studies, which suggests that there is no involvement of more relevant genes that can trigger uncontrolled clonal proliferation, but that generates immunological deregulation that could justify a greater risk of serious infection in these individuals.

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Biomedica

Título del artículo:

Prediction of patient admission and readmission in adults from a Colombian cohort with bipolar disorder using artificial intelligence

Introduction: Bipolar disorder (BD) is a chronically progressive mental condition, associated with a reduced quality of life and greater disability. Patient admissions are preventable events with a considerable impact on global functioning and social adjustment. While machine learning (ML) approaches have proven prediction ability in other diseases, little is known about their utility to predict patient admissions in this pathology. Aim: To develop prediction models for hospital admission/readmission within 5 years of diagnosis in patients with BD using ML techniques. Methods: The study utilized data from patients diagnosed with BD in a major healthcare organization in Colombia. Candidate predictors were selected from Electronic Health Records (EHRs) and included sociodemographic and clinical variables. ML algorithms, including Decision Trees, Random Forests, Logistic Regressions, and Support Vector Machines, were used to predict patient admission or readmission. Survival models, including a penalized Cox Model and Random Survival Forest, were used to predict time to admission and first readmission. Model performance was evaluated using accuracy, precision, recall, F1 score, area under the receiver operating characteristic curve (AUC) and concordance index. Results: The admission dataset included 2,726 BD patients, with 354 admissions, while the readmission dataset included 352 patients, with almost half being readmitted. The best-performing model for predicting admission was the Random Forest, with an accuracy score of 0.951 and an AUC of 0.98. The variables with the greatest predictive power in the Recursive Feature Elimination (RFE) importance analysis were the number of psychiatric emergency visits, the number of outpatient follow-up appointments and age. Survival models showed similar results, with the Random Survival Forest performing best, achieving an AUC of 0.95. However, the prediction models for patient readmission had poorer performance, with the Random Forest model being again the best performer but with an AUC below 0.70. Conclusion: ML models, particularly the Random Forest model, outperformed traditional statistical techniques for admission prediction. However, readmission prediction models had poorer performance. This study demonstrates the potential of ML techniques in improving prediction accuracy for BD patient admissions.

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Frontiers in Psychiatry

Título del artículo:

Delta power during sleep is modulated by EEG-gated auricular vagal afferent nerve stimulation (EAVANS)

Vagus nerve stimulation (VNS) has many clinical applications under development. In particular, there is a large interest in transcutaneous auricular VNS (taVNS) because it is non-invasive and provides easy access to neuromodulation. The present study proposes a novel approach for electroencephalography (EEG)-gated taVNS, with the ultimate goal of enhancing therapeutic outcomes, including for the treatment of delirium. Delirium arises from an altered state of consciousness and is the most common neuropsychiatric disorder observed in hospitalized patients, especially the elderly. Delirium has been linked to specific disturbances in EEG rhythms. Here, we propose an EEG-gated auricular vagal afferent nerve stimulation (EAVANS) approach to deliver stimulation targeting a specific instantaneous phase of the EEG Delta rhythm to modulate arousal and downstream reduction of neuroinflammation, two of the contributing factors to delirium. We hypothesize that treatment with EAVANS will modulate Delta power, which has been linked with delirium. As dominant Delta power is also a typical feature of non-rapid eye movement (NREM) sleep, we applied a prototype of an EAVANS device on healthy volunteers during sleep to establish preliminary validation. We successfully employed our closed-loop approach to target vagal afference during the rising Delta phase in the range [-π/2 0] radians. We found a significant reduction in Delta wave power for stimulation during the rising Delta phase compared to 1) absence of stimulation, 2) active stimulation during the descending Delta phase, and 3) active stimulation targeting non-vagal territory (i.e. greater auricular nerve) during the rising Delta phase. Further validation of our EEG-gated taVNS approach in the peri-operative period will be needed. As there is presently a lack of effective treatments for delirium, our non-pharmacological and non-invasive approach, if validated, could be easily deployed in clinical settings.Clinical Relevance-Given the serious health consequences and costs associated with delirium, and the absence of effective non-pharmacological treatments, the proposed neuromodulatory approach may be a promising option for reducing delirium and other disorders of consciousness. Our EAVANS prototype system has been tested on healthy volunteers during a NREM sleep state and will require further validation in different patient populations to optimize the proposed technology and gather more evidence to support its clinical utility. This novel non-pharmacological and non-invasive closed-loop neuromodulatory device could be used peri-operatively and in inpatient hospital settings to treat patients at risk of developing delirium. For instance, in a pre-operative setting, this technology may provide an effective preventative \'pre-habilitation\' approach for patients at high risk of developing delirium. Post-operatively, our technology may help manage patients with delirium more effectively.

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Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Título del artículo:

Comparative efficacy of three anesthetic protocols on cardiac parameters during ovary-hysterectomy in bitches

This study aimed to compare the general electrical heart activity, blood pressure, and heart rate when using three anesthetic protocols for ovariohysterectomy in bitches. In total, 33 healthy canines were selected, distributed in 3 groups of 11 animals each, aged between 1 and 3 years, and with a body weight of 8 to 15 kg from shelters in Bucaramanga, Colombia. Three anesthetic protocols in a completely randomized experimental designwere used. Protocol 1: Ketamine (7 mg/kg) + pentobarbital sodium (1 mg/kg); Protocol 2: Ketamine (7 mg/kg) + propofol (3 mg/kg); Protocol 3: Tiletamine + zolazepam (7 mg/kg). The individual outcomes were classified according to the American Society of Anesthesiologists (ASA I). The results showed that parameters evaluated in the surgical phase significantly increased in patients with Protocol 1 (p<0.05). Protocol 2 showed a better performance in the post-surgical phase (p<0.05) compared with others. Patients with Protocol 3 presented fewer alterations in the electrical conduction of cardiac activity than the other protocols, and quicker recovery after the surgery.

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Revista de Investigaciones Veterinarias del Peru

Título del artículo:

Factors that affect the productivity and competitiveness of the Faculty of Economics, Administrative and Accounting Sciences of the UDES Cúcuta within the framework of the Knowledge Economy.

In the teaching-learning process, the curriculum is a regulatory system that guides and regulates the theoretical-practical balance of the educational process, which is developed by higher education institutions to generate knowledge and offer added value to the productive sector; precision that originated the idea of this article whose objective is to analyze the Factors that affect the productivity and competitiveness of the Faculty of Economic, Administrative and Accounting Sciences of the UDES Cúcuta within the framework of the Knowledge Economy; Its elaboration is based on a qualitative criterion methodology within a documentary investigation that analyzed the consultancies on the subjects of knowledge and interest for the present work, making possible the analysis of the conceptual foundations and the analysis of the results referring to the gaps between expectations of entrepreneurs and added value of the graduates of the Financial Administration, Public Accounting, Marketing and Advertising and Foreign Trade programs, based on the pertinent factors that affect the productivity and competitiveness of the programs, which led to the conclusion of that UDES, Cúcuta must restructure the curriculum and the institutional educational project according to areas of knowledge proposed through an action plan.

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Aibi, Revista de Investigacion Administracion e Ingenierias

Título del artículo:

Images in Clinical Tropical Medicine Dermatological Features as a Diagnostic Clue in Systemic Loxocelism Caused by Brown Recluse Spider Bite

Acerca de la revista donde se publicó este artículo:

American Journal of Tropical Medicine and Hygiene

Título del artículo:

Analysis of the management of organic solid waste in Colombian companies based on the information from the industrial environmental survey EAI-2019

Introduction: This article reveals the problem of waste management by activities of companies and the destination given using the most recent information obtained from the industrial environmental survey EAI-2019 available through the National Administrative Department of Statistics (DANE). Materials and Methods: This study focuses on the amount of organic waste and its destination. For this, the variables are correlated: amount of organic waste and number of companies that take advantage of it for reuse according to the type of main activity of the companies. Results and Discussion: It was shown that only 65% of the companies measure the waste generated. The greater the amount of organic waste generated, the greater the amount that companies take advantage of for reuse, recycling or another modality. The predominant action is to deliver the waste to a third party that is in charge of the final destination with 56.9% of the companies, a figure that exceeds the 40.3% obtained from the sum of selling, donating or taking advantage of organic waste. Conclusions: There is evidence of a risk for measuring compliance with circular economy goals and for municipal development plans, taking into account that around 35% of companies do not measure waste. The commitment of companies to improve the volume of use of solid waste, even these can generate additional economic or energy resources according to the given destination. A good use of organic waste will contribute to the management of the circular economy to support the care of the environment.

Acerca de la revista donde se publicó este artículo:

Innovaciencia

Título del artículo:

Parameters estimation in Rasch models for estimation of food insecurity in a population.

Introduction: The Food Insecurity Experience Scale is a methodological proposal of the Voices of the Hungry Project of the FAO Statistics Division; is a set of questions whose objective is the measurement of food insecurity as a latent trait. This question module can be included in a survey, then with the response matrix, is possible to calculate prevalences of food insecurity through a Rasch model using the sum of the affirmative answers obtained by a person to the questions of the FIES module as a sufficient statistic for the estimation of the latent trait: Food insecurity. Methodology: A response matrix to the FIES module was simulated in R. Then a Rasch model was applied to this response matrix in order to obtain the theta and beta parameters according to different inferential frameworks: maximum likelihood, Bayesian, marginal and conditional, different R packages were used according to each estimation. Results: The estimation of the parameters θ according to maximum likelihood and conditional estimation are not appropriate to estimate extreme scores. Conclusions: Bayesian and marginal estimation allow extreme scores for parameters θ, however, have high computational cost. The conditional estimate, which is the estimate currently used in the analytical protocol of the FIES scale at a global level, use pseudo scores to estimate the θ0 and θ8 and is the recommended estimation process if the severity of the latent trait in individuals/ households is the estimation required.

Acerca de la revista donde se publicó este artículo:

Innovaciencia

Título del artículo:

Analysis of academic performance from a binary logistic regression model

Introduction: Comprehending the factors influencing students\' academic performance holds significant importance for the Universidad de Santander. This understanding enables the university to implement curricular adjustments and adaptations, which play a fundamental role in fostering the development of student competencies. Consequently, these adjustments contribute to enriching educational processes, thereby aiding in the successful fulfillment of the educational system\'s mission. Objective: To examine the factors influencing the academic performance of incoming students as opportunities for improvement that address the students\' needs. Materials and Methods: This study adopts an exploratory and cross-sectional design. Its comprised 1,161 new students. The response variable under consideration is the academic average attained by students at the conclusion of the academic semester. Data were sourced from national educational tests and institutional information systems. It was performed a statistical analysis using binary logistic regression, employing SPSS version 26 for the statistical software. Results and Discussion: An analysis of variance ANOVA F (2) = 24.94, p<.001 was performed, finding significant differences between the means of the average in the three campuses. The bivariate analysis using the Χ2(2) test = 26.72, p<.001, indicates that there is a statistically significant association between the academic average and the campus to which the students belong. Furthermore, the competencies assessed by the Saber 11 test, particularly the performance levels achieved in English and mathematics, were identified as crucial factors for the estimation of the academic performance model through binary logistic regression. Conclusions: Students who enter college with a stronger foundation in mathematics, critical reading, citizenship, and English proficiency experience enhanced consolidation within the college teaching and learning environment.

Acerca de la revista donde se publicó este artículo:

Innovaciencia

Título del artículo:

Panorama of nursing research production in Colombia

Acerca de la revista donde se publicó este artículo:

Revista Cuidarte

Título del artículo:

Validation of Nursing Outcome Indicators in Patients with Postsurgical Delirium

Objective. To validate the content of the indicators proposed from the Nursing Outcome Classification in a care plan for delirium management in older adults. Methods. Content validity study, conducted under the expert judgment technique. The procedure was developed in five moments: organization of indicators that respond to the nursing outcome classification for delirium management, support with literature of the indicators that responds to the result, selection of experts, establishment of agreements, and discussion. Quality criteria evaluated: pertinence and relevance, the Content Validity Coefficient and average scores assigned by the experts were calculated. Results. The study had the participation of 14 experts. The indicators, according to criteria of pertinence and relevance evaluated by experts showed a global average content index value of 0.93; 97.05% (66) of the indicators had Content Validity Coefficient?> 0.75. Conclusion. The quantitative findings of the indicator validation process showed high relevance and pertinence index, which favors their being applied to measure care changes in patients with delirium. Descriptors: validation study; delirium; adults; standardized nursing terminology; critical care units.

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Investigacion y Educacion en Enfermeria

Título del artículo:

Waist circumference cut-off points to identify major cardiovascular events and incident diabetes in Latin America: findings from the prospective Urban rural epidemiology study Colombia

Background: Abdominal obesity (AO) indirectly represents visceral adiposity and can be assessed by waist circumference (WC) measurement. In Latin America, cut-off points for the diagnosis of AO are based on Asian population data. We aim to establish the WC cut-off points to predict major cardiovascular events (MACE) and incident diabetes. Methods: We analyzed data from the cohort PURE study in Colombia. WC cut-off points were defined according to the maximum Youden index. Multivariate logistic regression was used to obtain associations between WC and MACE, diabetes, and cumulative incidence of outcomes visualized using Kaplan-Meier curves. Results: After a mean follow-up of 12 years, 6,580 individuals with a mean age of 50.7 ± 9.7 years were included; 64.2% were women, and 53.5% were from rural areas. The mean WC was 85.2 ± 11.6 cm and 88.3 ± 11.1 cm in women and men, respectively. There were 635 cases of the MACE composite plus incident diabetes (5.25 events per 1,000 person-years). Using a cut-off value of 88.85 cm in men (sensitivity = 0.565) and 85.65 cm in women (sensitivity = 0.558) resulted in the highest value for the prediction of the main outcome. These values were associated with a 1.76 and 1.41-fold increased risk of presenting the composite outcome in men and women, respectively. Conclusions: We defined WC cut-off points of 89 cm in men and 86 cm in women to identify the elevated risk of MACE and incident diabetes. Therefore, we suggest using these values in cardiovascular risk assessment in Latin America.

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Frontiers in Cardiovascular Medicine

Título del artículo:

Levy Rincón: the irascible opinion on YouTube

The article is based on the research \"Analysis of the content of the channels on YouTube, produced by Colombian independent video columnism\", whose general objective is to characterize the production of alternative opinion in Colombia, which is disseminated through the platform previously mentioned. The theoretical foundation that supports it is the academic literature related to the YouTube social media, where content different from that of the mainstream media circulates, and news values, a line of research in journalism studies. The methodology used was Content Analysis, with an Intercode Reliability and a Cohen\'s Kappa Coefficient of 20% of the sample. It concludes with the identification of 44 ways of expressing anger, mockery, criticism, and arguments, that the video columnist Levy Rincón uses in the production of his content, with a majority presence of two news values: prominence and negativity. In addition, with the construction of an opinion, whose content reuses the media production and uses different forms of argumentation.

Acerca de la revista donde se publicó este artículo:

Observatorio

Título del artículo:

Higher education in Colombia: a reading of its educational policies aimed at teacher training and its didactic methods (1991 - 2016)

This paper aims to analyze didactic trends and university teacher training in Colombia, considering higher education policies from 1991 to 2016. Research, laws, and decrees focused on teacher training and its didactics methods are analyzed. It was evident that the different governments of the day have been implementing reforms in higher education, to improve the quality of teacher training. The analysis of the trends showed that Colombia in terms of education policies, the Constitution of 1991 and Law 30 of 1992, have not been sufficient to respond to the millennium change, in educational quality, research processes, and improvement of coverage education. Regarding didactic trends in teacher training, during the period 2001-2016, the law does not contemplate the issue of didactics.

Acerca de la revista donde se publicó este artículo:

Estudios Pedagogicos

Título del artículo:

Structural analysis and cytotoxic evaluation of kisspeptin10 and analogs in types of cancer

The Kisspeptin system is a peptidergic system that plays a crucial role in regulating of reproduction and hormonal function. Kisspeptin is a peptide synthesized from the KiSS-1 gene and has been identified as the endogenous ligand of the kisspeptin receptor (KISS1R or GPR54 receptor). This system plays a key role in activating sex hormone secretion and puberty. In addition to its function in the regulation of reproduction, the Kisspeptin system has been found to play a role in other physiological processes, such as the regulation of appetite, energy metabolism, cardiovascular function, and cancer. In this study, several Kisspeptin analogs with structural modifications were designed and synthesized. The Kisspeptin analogs were evaluated by in vitro cytotoxicity tests on cancer cells of different cancer types. Cell viability assays were performed, and the concentrations that inhibited cell growth by a significant percentage were determined. The results showed that certain Kisspeptin analogs exhibited increased selective cytotoxicity in cancer cells compared to healthy cells. In conclusion, this study demonstrates that structurally modified Kisspeptin analogs have the potential to be therapeutic agents against some types of cancer. Understanding the structure-activity relationship of these analogs and their evaluation of their selective toxicity on cancer cells will be of great importance.

Acerca de la revista donde se publicó este artículo:

Bionatura