Título del artículo:

Exploring endosymbionts and pathogens in Rhipicephalus sanguineus and Ctenocephalides felis felis with Oxford Nanopore Technology

Fleas and ticks play a crucial role in public health as vectors of multiple diseases affecting humans and animals. Several rickettsial pathogens and endosymbionts are transmitted by fleas and ticks. Therefore, understanding this group of microorganisms is essential for fully grasping the spectrum of pathogens transmitted by vectors and the interactions between endosymbiotic microorganisms and their hosts. This study evaluated the presence and diversity of Rickettsiales species in fleas and ticks collected from the Santander department in Colombia. For the methodology a 16S gene amplification approach through Oxford Nanopore sequencing technologies in Rhipicephalus sanguineus and Ctenocephalides felis felis was used. Our findings revealed the presence of multiple pathogenic and endosymbiotic microorganisms, particularly from the Rickettsia and Wolbachia groups. We observed a clear association between Rickettsia species and ticks, while Wolbachia was predominantly found in fleas. Additionally, other important microorganisms were identified, including Anaplasma phagocytophilum, Rickettsia conorii, and different strains of Wolbachia that serve as endosymbionts in various arthropods. These results underscore the importance of fleas and ticks in the transmission of both pathogenic and endosymbiotic microorganisms. The distinct patterns of association between specific pathogens and vectors provide insight into their transmission dynamics. Identifying pathogens such as Anaplasma phagocytophilum and Rickettsia conorii further highlights the need for continued research into vector-borne diseases in Colombia. Understanding the interactions between endosymbionts and pathogenic microorganisms in these vectors could lead to the development of more effective strategies for controlling diseases transmitted by fleas and ticks.

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Research in Veterinary Science

Título del artículo:

Pioneering zero-waste technologies utilization and its framework on sustainable management: international, national and state level

Advancing decentralized waste valorization systems for circular economy integration and enhanced resource recovery. Transforming organic waste into high value bio products through scalable, innovative bioprocessing technologies. Integrating zero-waste solutions into urban planning to build resilient, climate-positive circular cities.

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Discover Applied Sciences

Título del artículo:

Secondary Prevention Medications in 17 Countries Grouped by Income Level (PURE): A Prospective Cohort Study

Background: It is unclear whether global use of medications for secondary cardiovascular (CVD) prevention is improving over time. Objectives: This study across 17 high-, middle- and low-income countries described variations in secondary CVD prevention medication use over a median follow-up of 12 years. Methods: In the multinational PURE (Prospective Urban Rural Epidemiology) cohort study, we conducted a repeated cross-sectional analysis to examine temporal variations in the use of secondary prevention medications in participants with CVD. In participants with coronary artery disease, we focused on antiplatelet agents, statins, renin-angiotensin system (RAS) inhibitors, and β-blockers. In participants with stroke, we focused on antiplatelet agents, statins, RAS inhibitors, and other blood pressure–lowering drugs. Medications were collected at baseline and on 4 subsequent follow-up visits. Results: The analysis included 7,409 participants with a diagnosis of CVD at the baseline visit, 8,792 at the second visit, 9,236 at the third visit, 11,082 at the fourth visit, and 11,677 at the last visit. The median age at baseline was 58.0 years, and 52.9% of the participants were female. The median follow-up was 12 years, with the median year of the baseline visit in 2007 and the fifth visit in 2019. Over this period, use of 1 or more classes of medications for secondary CVD prevention was 41.3% (95% CI: 40.2%-42.4%) at baseline, peaked at 43.1% (95% CI: 42.0%-44.1%), and then decreased to 31.3% (95% CI: 30.4%-32.1%) by the last study visit. In high-income countries, this use decreased from 88.8% (95% CI: 86.6%-91.0%) to 77.3% (95% CI: 74.9%-79.6%). In upper-middle-income countries, this use increased from 55.0% (95% CI: 52.8%-57.3%) to 61.1% (95% CI: 59.1%-63.1%). In lower-middle-income countries, use of at least 1 class of medications was 29.5% (95% CI: 28.1%-30.9%) at baseline, peaked at 31.7% (95% CI: 30.4%-33.1%), and then decreased to 13.4% (95% CI: 12.5%-14.2%) by the last visit. In low-income countries, use of at least 1 class of medications was 20.8% (95% CI: 18.1%-23.5%) at baseline, peaked at 47.3% (95% CI: 44.8%-49.9%), and then decreased to 27.5% (95% CI: 25.2%-29.9%) by the last study visit. Conclusions: Globally and in most country income-level groups, the use of medications for secondary CVD prevention has been low, with little improvement over time.

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Journal of the American College of Cardiology

Título del artículo:

Evaluation of dengue virus seroprevalence in four boroughs of Mexico City among persons aged 5-35 years in 2022

Introduction: Dengue is currently the most widespread vector-borne disease, and its transmission has been intensively studied in endemic/hyperendemic localities. However, to obtain a complete picture of dengue transmission, it is necessary to study nonendemic localities. Imported dengue cases have been reported in Mexico City, and the presence of eggs of the vector Aedes aegypti has been detected. Methodology: In the present study, we determined the prevalence of IgG antibodies against Dengue virus in four city boroughs via random cluster sampling in individuals aged 5-35 years. Results: The weighted seroprevalence rate was 1.90% (95% CI 0.75-4.75) at Xochimilco, 1.81% (95% CI 0.64-5.00) at Venustiano Carranza, 1.81% (95% CI 0.54-5.83) at Tlahuac, and 5.48% (95% CI 1.96-14.43) at Gustavo A Madero; seropositivity was concentrated in the adult group, many of whom lived in dengue-endemic localities. The distribution of seroprevalence in the four boroughs is very homogeneous and unrelated to the number of vector eggs in the borough. Conclusions: These data suggest that there is still no autochthonous transmission of dengue in Mexico City. However, it is important to note that the structural conditions of the dwellings in these boroughs, which offer minimal barriers to vector infestation, could facilitate the establishment of local transmission under favorable conditions.

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Journal of Infection in Developing Countries

Título del artículo:

Cardiovascular disease in the Americas: optimizing primary and secondary prevention of cardiovascular disease series: cardiovascular disease in the Americas

While, many interventions can prevent cardiovascular disease (CVD), and its resulting morbidity or mortality, these are used sub-optimally in most countries. Therefore, health systems need to develop new approaches to ensure that proven CVD therapies are delivered widely. In this review, we describe five impactful implementation strategies which include: (1) Task shifting, (2) Use of mobile-Health (mHealth) support and virtual access to care, (3) simplified diagnostic and management algorithms for the prevention of CVD, (4) improving the use of combinations of medicines (i.e., polypill), and (5) patient engagement and role of patient-nominated peer support (i.e., treatment supporters). Adapting and tailoring these strategies to the local context in different settings in various countries in the Americas and the Caribbean can reduce the morbidity and mortality of CVD substantially.

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The Lancet Regional Health - Americas

Título del artículo:

Cardiovascular disease in the Americas: the epidemiology of cardiovascular disease and its risk factors

This first article of the Series about Cardiovascular Disease in the Americas summarizes the epidemiology of CVD and its risk factors, and population-level strategies in place aimed at CVD prevention. While age-standardized CVD incidence and CV mortality rates have been decreasing across in the Americas since 1990, the annual number of CVD cases and related deaths have increased due to population growth and ageing. The burden of CVD is also slowly transitioning from high-income countries in North America to middle-income countries in Latin America and the Caribbean. Trends in CV risk factor levels have been mixed, with declines in smoking and mean cholesterol counterbalanced by higher prevalence of obesity and diabetes. Population-wide strategies aimed at controlling cardiometabolic risk factors and tobacco use have been implemented with varying degrees of success. There is a need to better implement existing CVD prevention strategies in the region.

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The Lancet Regional Health - Americas

Título del artículo:

Perceptions of Barriers to Inclusion in Students with Disabilities in Higher Education Institutions

This study aimed to analyze the perceptions of students with disabilities regarding the barriers to inclusion in higher education institutions in northeastern Colombia. Employing a mixed-methods approach, data were collected through questionnaires and semi-structured interviews with 28 students with disabilities, focusing on socio-demographic data and their personal university experiences. The findings revealed that physical and visual impairments were the most common (34.6% each) and the primary barriers were insufficient pedagogical strategies. An association between the type of disability and perceived support was identified. In conclusion, this study enabled the development of a comprehensive model for university inclusion in the northeastern region.

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Societies

Título del artículo:

Is Early and Recurrent Anemia in a Preterm Infant a Risk Factor for Neonatal Appendicitis?

Background: Neonatal appendicitis (NA) is a rare condition with an estimated incidence of 0.04% to 0.2%. It is more prevalent in male preterm infants, with a mortality rate of 20% to 25%. It is usually misdiagnosed as neonatal necrotizing enterocolitis (NEC) owing to its diverse diagnostic challenges. Poor perfusion, hypoxia, anemia, or any other condition that impairs intestinal blood supply is a risk factor for bowel injury, which could explain the physiopathology of NA. Clinical Findings: We describe an interesting case of a preterm infant with recurrent episodes of abdominal distension and persistent anemia who was finally diagnosed with NA. Primary Diagnosis: The patient was treated with exploratory laparotomy and appendicectomy, with further symptom resolution. The diagnosis was confirmed by pathological examination. Interventions: Surgery for acute abdomen secondary to perforated appendicitis. Outcomes: Improved recurrent abdominal distension and persistent anemia and achieved full enteral nutrition. Patients with other diseases such as Hirschsprung\'s disease were ruled out. Practice Recommendations: This case demonstrates that identifying the early signs and symptoms of NA requires a high index of suspicion. Anemia may play a significant role in the etiology of intestinal injury, increasing the risk of NA and NEC. Further studies are needed to explore the association between anemia and intestinal injury and its implications for neurodevelopment.

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Advances in Neonatal Care

Título del artículo:

Methodological and reporting quality of Latin American randomized controlled trials in surgery from 2012 to 2022: a meta-research study

Background: Latin America is a region where an increasing number of randomized controlled trials (RCTs) in surgery are being conducted. However, there is no evidence regarding the methodological and reporting quality of this studies. Methods: Meta-research study, including RCTs conducted in general surgery and subspecialties, conducted in Latin American centers and published from 2012 to 2022 with inclusion in PubMed and Scopus databases. The CONSORT and Joanna Briggs Checklist for Randomized Controlled Trials tools were used. Results: 83 RCTs met the inclusion criteria. 67.5% (n = 56) were conducted in Brazil. 74.7% (n = 62) of RCTs demonstrated high methodological quality, while only 31.7% (n = 26) exhibited high reporting quality. Out of the 13 methodological quality items, 3 were not fulfilled in more than 50% of the RCTs. Meanwhile, of the 37 reporting quality items, only 15 were met in more than 75% of the RCTs. Conclusions: While the methodological quality of Latin American RCTs in surgery included in PubMed and Scopus is relatively high, there is a predominance of moderate reporting quality. The common failure to comply with specific items in this sample is a phenomenon of great interest for surgical meta-research that warrants deeper exploration. These shortcomings the falsifiability and reproducibility of Latin American RCTs in surgery, which could be improved through scientific training.

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International Journal of Surgery Open

Título del artículo:

Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries

The consumption of sugar-sweetened beverages (SSBs) is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). However, an updated and comprehensive assessment of the global burden attributable to SSBs remains scarce. Here we estimated SSB-attributable T2D and CVD burdens across 184 countries in 1990 and 2020 globally, regionally and nationally, incorporating data from the Global Dietary Database, jointly stratified by age, sex, educational attainment and urbanicity. In 2020, 2.2 million (95% uncertainty interval 2.0–2.3) new T2D cases and 1.2 million (95% uncertainty interval 1.1–1.3) new CVD cases were attributable to SSBs worldwide, representing 9.8% and 3.1%, respectively, of all incident cases. Globally, proportional SSB-attributable burdens were higher among men versus women, younger versus older adults, higher- versus lower-educated adults, and adults in urban versus rural areas. By world region, the highest SSB-attributable percentage burdens were in Latin America and the Caribbean (T2D: 24.4%; CVD: 11.3%) and sub-Saharan Africa (T2D: 21.5%; CVD: 10.5%). From 1990 to 2020, the largest proportional increases in SSB-attributable incident T2D and CVD cases were in sub-Saharan Africa (+8.8% and +4.4%, respectively). Our study highlights the countries and subpopulations most affected by cardiometabolic disease associated with SSB consumption, assisting in shaping effective policies and interventions to reduce these burdens globally.

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Nature Medicine

Título del artículo:

Altered parasympathetic outflow and central sensitization response to continuous pain in cyclic vomiting syndrome: a functional magnetic resonance imaging study

Cyclic vomiting syndrome (CVS) is a disorder of brain-gut interaction characterized by recurrent episodes of nausea and vomiting interspersed with asymptomatic periods and associated with autonomic nervous system dysfunction. We examined the dysautonomic response to noxious stimuli for patients with CVS using our previously validated approach to integrate peripheral autonomic outflow metrics, temporal summation of pain, and brain functional MRI (fMRI). Blood oxygen level-dependent (BOLD) fMRI and ECG were acquired from patients with CVS and healthy adults during both a rest condition and a sustained cuff pressure-pain stimulus at the leg. After the latter scan, participants rated pain for the first, middle, and last 2 min to calculate temporal summation. During sustained pain, patients, relative to healthy controls, exhibited greater reduction in heart rate variability within the high-frequency range (HF-HRV) and reduced anticorrelation between HF-HRV and fMRI signal in the anterior insula, pregenual anterior cingulate cortex, and ventrolateral and dorsolateral prefrontal cortex. Compared with healthy adults, patients also exhibited increasing pain intensity over the course of sustained cuff pressure. For healthy adults, seed-based functional connectivity analysis revealed pain sensitization correlated with pain-induced increases in connectivity between primary somatosensory cortex and regions of interest in both left anterior insula/posterior orbitofrontal cortex and right presupplementary motor area. These correlations were not seen in CVS, thus supporting a conclusion of altered central coding of nociceptive stimuli and autonomic responsivity of patients with CVS in key brain regions implicated in autonomic control and interoception.NEW & NOTEWORTHY Patients with cyclic vomiting syndrome exhibit multiple alterations in central function in response to a sustained pressure-pain stimulus, including altered high-frequency heart rate variability and associated changes in BOLD fMRI signal in key areas of the central autonomic and interoceptive networks, as well as abnormal temporal summation of pain associated with altered connectivity patterns between the primary somatosensory cortex and key regions associated with interoception.

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American journal of physiology. Gastrointestinal and liver physiology

Título del artículo:

Women With Polycystic Ovary Syndrome and Excess Body Fat Exhibit Atypical Sympathetic Autonomic Modulation That is Partially Reversed by Aerobic Physical Training

Objective: The aetiology of impairments in autonomic modulation of heart rate variability (HRV) in polycystic ovary syndrome (PCOS) remains unclear, as does the impact of aerobic physical training (APT) on controlling endocrine-metabolic disorders and HRV. This is because these women often present excess body fat. Therefore, we assessed whether the dysregulation in autonomic modulation of HRV in women with PCOS is due to endocrine-metabolic disorders and whether the combination of excess body fat with endocrine-metabolic disorders amplifies cardiovascular autonomic deficits. We also investigated whether APT positively influences autonomic modulation of HRV in PCOS. Design: Non-randomised clinical trial. Participants: Women with and without PCOS with different percentages of body fat. Measurements: Participants were divided into four groups: women without PCOS with a body fat percentage between 22% and 29% (CONTROL group; 22%–29%); CONTROL (30%–37%) group; PCOS (22%–29%) group; and PCOS (30%–37%) group. Hemodynamic, metabolic, and hormonal characteristics and HRV parameters were obtained before and after 16 weeks of APT. Results: The PCOS (22%–29%) group exhibited lower vagal modulation than the CONTROL (22%–29%) group. In contrast, no significant differences were observed between the CONTROL (30%–37%) and PCOS (30%–37%) groups. Furthermore, the PCOS (30%–37%) group demonstrated lower sympathetic modulation than the PCOS (22%–29%) group. After APT, the PCOS (22%–29%) group increased in vagal modulation, while the PCOS (30%–37%) group increased in sympathetic modulation. Conclusion: PCOS affects vagal modulation; however, this effect may be masked at elevated levels of body fat. Additionally, the combination of excess body fat with endocrine-metabolic dysregulation appears to reduce sympathetic modulation, possibly due to sympathetic drive hyperactivity. APT positively affected HRV in both PCOS groups.

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Clinical Endocrinology

Título del artículo:

Community-based model for management and follow-up by non-physician healthcare workers to improve awareness, treatment, and control of hypertension: The COTRACO study protocol

Introduction: Cardiovascular diseases are the leading cause of death and morbidity worldwide, with a significantly higher burden in low- and middle-income countries. Hypertension, a major risk factor for cardiovascular morbidity and mortality, remains under-diagnosed and poorly controlled, especially in regions such as Latin America. The HOPE-4 study demonstrated that the involvement of non-physician health workers (NPHWs), the use of standardized treatment algorithms, the provision of free antihypertensive drugs and home follow-up can significantly improve hypertension control and reduce cardiovascular risk, as demonstrated in Colombia and Malaysia. On this basis, the COTRACO study aims to address the barriers to hypertension treatment in low- and middle-income countries by implementing a similar standardized treatment approach delivered by non-specialist health workers. Methodology: The COTRACO study is a quasi-experimental, parallel-group, non-randomized, before-and-after study. A community-based model will be implemented in 600 patients in Colombia and the Dominican Republic, involving NPHWs to: 1) apply standardized treatment algorithms, 2) promote adherence to healthy lifestyles, and 3) provide standardized pharmacological treatment. Propensity Score Matching will be used to select 300 patients in Chile and 1200 in Spain for comparison with standard care in these populations. Expected outcomes: The primary outcome at 12 months of follow-up is the percentage of patients achieving controlled hypertension (defined as systolic BP < 140 mmHg and diastolic BP < 90 mmHg, or < 130 mmHg, and diastolic BP < 80 mmHg for diabetic patients), ensuring it is not inferior to that achieved in the control countries. Secondary outcomes include changes in BP levels, cholesterol levels, BMI, handgrip strength, waist-to-hip ratio, smoking status, Interheart risk score, diet, and physical activity at 6 and 12 months. Recommendations: If this model demonstrates superior outcomes compared to usual care, it is recommended that health authorities in low- and middle-income regions adopt and implement this approach. Using non-medical health professionals, standardized treatment algorithms and free access to antihypertensive medications, these regions can significantly improve awareness, diagnosis and management of hypertension. This strategy has the potential to reduce cardiovascular morbidity and mortality, thereby improving overall public health outcomes.

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Heliyon

Título del artículo:

Beef cows with larger vulvar width have greater antral follicle count, viable oocytes, and higher circulating AMH

Owing to the low heritability of reproductive traits, the search for markers and their interrelationship that could indicate reproductively superior individuals is important in the selection process for bovine reproductive efficiency. This study aimed to investigate the possible interrelationships between the antral follicle count (AFC), vulvar-width (VW), anti-Müllerian hormone (AMH) concentrations, fertility in Bos Taurus and Bos Indicus females. Brahman (Bos Taurus-Indicus, n = 126) and Simmental and Angus (Bos Taurus-Taurus, n = 155) cows were classified as having large (≥86 mm) and small (<86 mm) VW. From each group, one blood sample per animal was collected to determine the AMH serum concentrations. The GLIMMIX procedure in SAS® was used to determine whether vulva width (VW) and AMH classes, associated or not with breed, could influence the age at first calving (FCA), calving to first service interval (CFSI), calving interval (CI), number of services per pregnancy (SP), and number of viable oocytes (VO). Antral follicle count (AFC) (36.10 ± 1.90 vs. 22.78 ± 1.64, for large and small VW, respectively), AMH (1.17 ± 0.07 vs. 0.48 ± 0.007 ng/mL), and viable oocytes or VO (18.86 ± 1.76 vs. 10.15 ± 1.49) were greater (P < 0.05) in the large VW than in the small VW. Brahman cows had greater AFC (36.30 ± 1.34 vs. 22.09 ± 1.67), VW (106.94 ± 15.83 vs. 69.78 ± 14.11 mm), and AMH (1.18 ± 0.07 vs. 0.42 ± 0.05 ng/mL) compared to that of taurine cows. In conclusion, VW was an efficient predictor of AFC and AMH concentrations in both genetic groups, but under the conditions of this trial no link could be detected between these variables and the reproductive indices studied.

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Animal Reproduction

Título del artículo:

Effects of physical exercise on the lipid profile of perimenopausal and postmenopausal women: a systematic review and meta-analysis

During the climacteric period, the decline in ovarian hormones leads to changes in the lipid profile. Physical exercise is the main non-pharmacological recommendation for controlling lipid levels. However, the effects on the lipid profile in perimenopausal and postmenopausal women are incipient and inconclusive. In this context, we searched the Embase, PubMed, Scopus, and Web of Science databases for randomized clinical trials on the effects of exercise on the lipid profile of these women. We excluded studies that did not specify criteria for classifying the climacteric phase, that involved women undergoing hormone replacement therapy, or that examined combined treatments or acute effects of physical exercise. The meta-analysis indicated that general physical exercise increased high-density lipoprotein cholesterol (HDL-C) levels (mean difference [MD]=4.89; 95% confidence interval [95%CI]=0.97 to 8.81) in perimenopausal women. For obese postmenopausal women, 16 weeks of aerobic training increased HDL-C levels (MD=3.88; 95%CI=0.56 to 7.20) and reduced total cholesterol (MD=–22.36; 95%CI=–29.67 to –15.05) and low-density lipoprotein cholesterol (LDL-C) levels (MD=–17.86; 95%CI=–25.97 to –9.75), whereas 12 weeks of resistance training increased HDL-C levels (MD=4.20; 95%CI=1.16 to 7.23) and decreased triglycerides (MD=–14.86; 95%CI=–26.62 to –3.09) and LDL-C levels (MD=–16.36; 95%CI=–28.05 to –4.67). Overall, the results showed that physical exercise regulated lipid profiles in perimenopausal and postmenopausal women. Specifically, 12 weeks of resistance exercise and 16 weeks of aerobic exercise improved the lipid profile of obese postmenopausal women.

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Brazilian Journal of Medical and Biological Research

Título del artículo:

Adrenal insufficiency due to everolimus: a case report

Although rare, secondary adrenal insufficiency represents a serious complication in patients receiving treatment with mTOR inhibitors, such as everolimus. This drug is commonly used to prevent organ transplant rejection and to treat certain cancer types, but its impact on adrenal function is not always apparent. In the case presented, a 74-year-old man with a history of liver transplant and type 2 diabetes mellitus attended his routine medical check-up with no symptoms related to adrenal insufficiency. Despite his asymptomatic state, the medical team decided to study adrenal function because of the prolonged duration of everolimus treatment. The diagnostic tests included the measurement of 24-hour urine cortisol, which revealed low cortisol levels, thus confirming adrenal insufficiency. This finding is significant, as adrenal insufficiency can result in adrenal crises that, if not properly managed, can be potentially fatal. This case highlights the importance of endocrine surveillance in immunosuppressed patients, where the absence of symptoms should not lead to complacency. A proactive approach to evaluating adrenal function is crucial for identifying complications before they become emergencies. Early detection and appropriate treatment of adrenal insufficiency can significantly improve clinical outcomes and the quality of life for these patients. Therefore, it is recommended that physicians remain vigilant to the risks associated with the use of mTOR inhibitors and conduct regular adrenal function evaluations in this patient group.

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Horizonte Medico

Título del artículo:

Human-Oriented Fuzzy-Based Assessments of Knowledge Graph Embeddings for Fake News Detection

In the era of information overload, distinguishing between real and fake news is a critical challenge, particularly in public social networking domains. For this purpose, an approach based on the synergy accomplished by a Neurosymbolic AI system, powered with Fuzzy Logic techniques, is introduced to achieve understandable fact-checking classification results. The work proposes a fact-checking approach based on Knowledge Graph Embedding (KGE) techniques. It extracts the involved entities from textual data in the form of triples that, projected in a vector space, form graphs that effectively highlight contextual information. The classification results are interpreted by exploiting fuzzy set modelling, which aims to improve the presentation of the final results. Specifically, we use the Hits@N metric to design fuzzy variables whose linguistic terms reflect news distribution. Then, by exploiting fuzzy rule design, human-like classification performance evaluation is provided. Through experimental evaluation of the benchmark dataset, our approach shows its effectiveness in discriminating between real and fake news, enhanced by straightforward explanations driven by the fuzzy rule design.

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Lecture Notes in Networks and Systems

Título del artículo:

Cardiovascular effects of household air pollution on cardiovascular diseases incidence

Cardiovascular diseases (CVD) are the main cause of death globally, especially in low- and middle-income countries (LMICs), where the largest number of inhabitants on the planet are concentrated. Air pollution inside and outside the home by microparticles 2 5 (PM2·5) has become an important risk factor for the presence of CVD and other chronic non-communicable diseases, particularly in LMICs. The use of solid fuels as an energy source for cooking food and heating inside the home has negative effects not only on human health but also on the health of the planet, as it contributes to deforestation and the consequent effect on climate change. In this narrative review we update how air pollution inside the home from cooking food with firewood and charcoal impacts the risk of CVD, the factors that determine the use of these polluting fuels, and the actions necessary for the massive transition toward the use of non-polluting energy, highlighting the development of university research to offer a stove that uses green hydrogen as a non-polluting energy source.

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Clinica e Investigacion en Arteriosclerosis

Título del artículo:

Knowledge, attitudes, prevention and opinion of nursing professionals regarding COVID-19: analytical study

Objective: to analyze the relationship between the knowledge, prevention, attitudes and opinion of nursing professionals in adult intensive care units regarding COVID-19 and their sociodemographic and work characteristics. Method: cross-sectional, analytical study. 124 nursing professionals who worked in adult intensive care units after the COVID-19 pandemic were included. To measure the variables, the Awareness, Attitudes, Prevention and Perceptions of COVID-19 Outbreak among Nurses questionnaire was used. To identify differences between the groups, the following tests were used: Kruskal-Wallis and Mann-Whitney U, Pearson correlation, and multiple analysis in logistic regression for each dimension. Results: participants with a workplace in private institutions showed a tendency towards better scores in awareness OR=3.92 (95%CI:1.50; 10.25), in prevention OR=8.93 (95%CI:3.12; 25.565), in attitude OR=2.77 (95%CI: 1.16; 6.58) and in perception with an OR= 19.65 (95%CI: 5.85; 65.94). In attitude, male participants showed a better result with OR=3.31 (95%CI: 1.18; 9.23) and in relation to perception, those who showed the best results were those with postgraduate studies as specialists OR=7.60 (95%CI: 1.73; 33.23). Conclusion: working in a private institution and having a postgraduate specialization degree were related to better scores in the dimensions of the scale.

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Revista Latino-Americana de Enfermagem

Título del artículo:

Comparison of dairy production based on feed of Pennisetum sp., Pennisetum purpureum and CIAT 36087

In dairy production systems, efficient pasture management is crucial for maximizing milk output while minimizing costs. However, many producers make decisions without considering the productive efficiency of different forage types. This research aims to address this gap by comparing the milk production and related expenses of Brown Swiss and Jersey cows fed with three types of grass: Maralfalfa (Pennisetum sp.), Cameroon (Pennisetum purpureum), and Mulato (CIAT 36087).The milk production and related expenses for generating one liter of milk from Brown Swiss and Jersey cows were compared when fed with Maralfalfa (Pennisetum sp.), Cameroon (Pennisetum purpureum), and Mulato (CIAT 36087) grasses. Productive and reproductive parameters affecting milk production were analyzed. Milk production of the cows under study was measured for one month when they were exclusively pasture–fed with Mulato grass. The group of 33 cows was randomly subdivided into three subgroups, each consisting of 11 cows, and each subgroup was assigned to consume a specific type of grass. This resulted in the Maralfalfa consumption group (SG1), the Cameroun consumption group (SG2), and the control group with Mulato pasture feeding (SG3). Daily milk production was recorded for six weeks, with standardized management and ad libitum feeding. Daily milk production for each cow was monitored and recorded over the six–week period. Highly significant differences (P<0.01) were observed among the three studied groups from the second week onward. The main difference was observed between SG1 and SG3. The highest productivity, with greater milk production volumes, was observed in cows consuming Maralfalfa. However, variables such as the service period, live weight, and number of calving performed better with Cameroon grass. Cost–benefit analysis favored the use of Mulato grass.

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Revista Cientifica de la Facultad de Veterinaria

Título del artículo:

Effectiveness of the advanced stop line for motorcycles in Bucaramanga validated by means of a logistic regression model

Road traffic accidents are a significant public health concern worldwide, and it is essential that individual countries adopt distinct safety measures to safeguard vulnerable road users. The objective is to analyze traffic accidents occurring at Motorcycle Advanced Stop Lines by applying a Logistic Regression model. When a traffic accident occurs, a motorcycle is involved and is 15 times more likely to be of high severity compared to accidents with other road users. The implementation of this initiative requires political will. Furthermore, technical studies should support to regulate horizontal and vertical signage, which can be included in Colombia\'s road signage manual in the future.

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Aibi, Revista de Investigacion Administracion e Ingenierias

Título del artículo:

Author Correction: Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries (Nature Medicine, (2025), 10.1038/s41591-024-03345-4)

Correction to: Nature Medicinehttps://doi.org/10.1038/s41591-024-03345-4, published online 6 January 2025. In the version of the article initially published, in the eighth paragraph of the Discussion, the text “Among large nations, the largest increases in SSB-related T2D burdens were in Mexico, Thailand and the United Kingdom, and in CVD burdens, Colombia, Nigeria, Thailand and Russia. These changes align with rises in SSB consumption in these nations12. Similarly, declining SSB-related cardiometabolic burdens in Brazil, the United States and the United Kingdom (for CVD) are consistent with their decreasing SSB consumption from 1990 to 202012” was incorrect and has now been updated to “Among largely populated nations, the largest increases in SSB-related T2D incidence was in Colombia, USA and Argentina; and in CVD incidence, Nigeria, Russia, Colombia and Thailand. These changes generally align with rises in SSB consumption in these nations, except in the US where slight declines in SSB consumption were offset by increased burdens of diabetes 12. Similarly, declining SSB-related cardiometabolic burdens in Turkey, Brazil, and the United States and the United Kingdom for CVD are consistent with their decreasing SSB consumption from 1990 to 202012.” Additionally, Supplementary Data 1 and 2 have been updated to remove decimals in values greater than 100. These corrections have been made to the HTML and PDF versions of the article.

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Nature Medicine

Título del artículo:

Biological properties of Moringa oleifera: A systematic review of the last decade

Background: The growing incidence of chronic diseases such as cancer and the emergence of drug-resistant microorganisms constitute one of the greatest health challenges of the 21st century. Therefore, it is critical to search for new therapeutic alternatives. Moringa oleifera is a plant well known for the properties of its phytocomponents and its role has been analyzed in a variety of fields, from medicine to biotechnology. Methods: In this work, the biological activity of Moringa oleifera in human health was explored through a review of 129 original articles published between 2010 and 2021 related to antitumor activity and its potential uses against chronic and infectious diseases. Results: Moringa oleifera extracts showed antioxidant, hypoglycemic, antihypertensive and cytoprotective properties at neuronal, hepatic, renal and cardiac levels. Besides, cytotoxic effects, apoptotic and antiploriferative activity against several cancer cell lines has been demonstrated. On the other hand, the antimicrobial potential of M. oleifera was also evidenced, especially against multidrug-resistant strains. Conclusions: Hence, it is supported that there is a wide range of clinical entities in which Moringa oleifera exhibits significant biological activity that could contribute to counteracting metabolic, infectious and chronic diseases in a similar or improved way to the drugs traditionally used.

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F1000Research

Título del artículo:

Efficiency of Graphene Quantum Dots in Water Contaminant Removal: Trends and Future Research Directions

This review explores the efficiency and mechanisms of GQDs in removing contaminants from water, emphasizing their potential for environmental applications. GQDs possess unique physicochemical properties, such as a high surface area, tunable photoluminescence, and strong adsorption capacities, which enable the effective removal of diverse contaminants, including heavy metals, organic compounds, and dyes. Their electron-hole separation efficiency and functionalizability enhance their reactivity and selectivity. Notable findings include the integration of GQDs into advanced nanocomposites and supramolecular networks, significantly improving their adsorption and catalytic performance. However, challenges such as variability in synthesis methods, stability under environmental conditions, and the environmental impact of GQDs remain. Addressing these limitations and understanding the interaction mechanisms between GQDs and contaminants are critical. Future research should prioritize scalable green synthesis techniques, long-term environmental assessments, and optimized functionalization strategies to establish GQDs as a sustainable solution in water purification technologies.

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Water (Switzerland)

Título del artículo:

The Impact of Artificial Intelligence in the World of Finance: A Bibliometric Study

The current research focuses on how artificial intelligence (AI) is influencing decision-making, risk management, and the provision of financial services in the financial industry. The use of sophisticated algorithms, big data analytics, and machine learning has transformed the process of making financial forecasts, detecting fraud, and making investments. Globally, technological innovation has improved the efficiency and availability of top-notch financial services, but it has also brought up moral and legal concerns. The goal of the study, which used a bibliometric technique and the Scopus database, was to identify new scientific trends about the impact of artificial intelligence on finance. The results showed that, in recent years, there has been a notable annual rise in scholarly production on this issue of 3.62%. 464 writers and 207 sources were found to be engaged in these articles; the number of authors increased noticeably in 2020, 2011 and 2023. With 14% of publications, China dominated the world in scientific productivity, followed by the US, India, and other nations. The most pertinent journals in this topic were Sustainability (Switzerland) and Lecture Notes in Networks and Systems, each of which had four articles. Universities that have contributed to the body of knowledge on this subject include Universitas Negeri Semarang, Uttaranchal University, and Spiru Haret University. Lebonte M., Irfan M., and Morrison were the most important authors; all three made a substantial impact. It was discovered that 2.29% of scientists working in this area interacted with scientists abroad. The report concludes by giving a summary of the current level of research on the effects of artificial intelligence in finance, highlighting areas of interest and emphasizing the significance of further research to solve problems and take advantage of opportunities in this rapidly developing field.

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Communications in Computer and Information Science